Tuesday, June 6, 2023
  • English
  • Marathi
No Result
View All Result
Daily PRABHAT
  • Home
  • Latest News
  • National
  • International
  • Entertainment
  • Politics
  • Sports
  • Business
  • More
    • Health
    • Lifestyle
    • Technology
    • Science
Daily PRABHAT
No Result
View All Result
  • Home
  • Latest News
  • National
  • International
  • Entertainment
  • Politics
  • Sports
  • Business
  • More
Home Lifestyle

Study finds antidepressants don’t improve quality of life long term

by Digital Desk
1 year ago
in Lifestyle
A A
Study finds antidepressants don’t improve quality of life long term
Share on FacebookShare on Twitter

Washington [US], April 23 (ANI): When comparing depressed people who don’t take antidepressants with those who do, it was found that usage of the drugs over time is not associated with significantly better health-related quality of life.

These were the findings of a recent study published in the open-access journal PLOS ONE by Omar Almohammed of King Saud University, Saudi Arabia, and colleagues.

It is generally well known that depression disorder has a significant impact on the health-related quality of life (HRQoL) of patients. While studies have shown the efficacy of antidepressant medications for the treatment of depression, these medications’ effect on patients’ overall well-being and HRQoL remains controversial.

In the new study, the researchers used data from the 2005-2015 United States’ Medical Expenditures Panel Survey (MEPS), a large longitudinal study that tracks the health services that Americans use. Any person with a diagnosis of depression disorder was identified in the MEPS files.

Over the duration of the study, on average there were 17.47 million adult patients diagnosed with depression each year with two years of follow-up, and 57.6 per cent of these received treatment with antidepressant medications.

The use of antidepressants was associated with some improvement in the mental component of SF-12 — the survey tracking health-related quality of life. However, when this positive change was compared to the change in a group of people who were diagnosed with the depressive disorder but did not take antidepressants, there was no statistically significant association of antidepressants with either the physical (p=0.9595) or mental (p=0.6405) component of SF-12. In other words, the change in the quality of life seen among those on antidepressants over two years was not significantly different from that seen among those not taking the drugs.

The study was not able to separately analyze any subtypes or varying severities of depression. The authors say that future studies should investigate the use of non-pharmacological depression interventions used in combination with antidepressants.

The authors add: “Although we still need our patients with depression to continue using their antidepressant medications, long-term studies evaluating the actual impact of pharmacological and non-pharmacological interventions on these patients’ quality of life is needed. With that being said, the role of cognitive and behavioural interventions in the long term-management of depression needs to be further evaluated in an effort to improve the ultimate goal of care for these patients; improving their overall quality of life.” (ANI)

ShareTweetSendShareSend

Latest News

Rs 200 crore extortion case: Delhi police files FSL report of Rohini Jail CCTV footage, says no alteration in videos

Mamata Banerjee arrives in Cuttack to meet victims of Balasore train accident

CBI registers case relating to train accident involving Coromandel Express, Yashwantpur-Howrah Express, Goods train in Odisha

Two arrested with gold worth Rs 1 cr hidden in rectum at Hyderabad airport

“We will be providing internet for all” with K-FON project launch: Kerala CM

CBI registers FIR in Coromandel Express train accident in Odisha, team visits site

Court sends Amritpal, Amrik Singh associated with Khalistani outfit KTF to judicial custody after NIA remand ends

Assam Education Council declares Class 12 result

Graphic novel ‘Ajay to Yogi Adityanath’ launched on UP CM’s 51st birthday

Assam: Students’ union stages protest against govt’s move to teach science, maths in English

Washington [US], April 23 (ANI): When comparing depressed people who don't take antidepressants with those who do, it was found that usage of the drugs over time is not associated with significantly better health-related quality of life.

These were the findings of a recent study published in the open-access journal PLOS ONE by Omar Almohammed of King Saud University, Saudi Arabia, and colleagues.

It is generally well known that depression disorder has a significant impact on the health-related quality of life (HRQoL) of patients. While studies have shown the efficacy of antidepressant medications for the treatment of depression, these medications' effect on patients' overall well-being and HRQoL remains controversial.

In the new study, the researchers used data from the 2005-2015 United States' Medical Expenditures Panel Survey (MEPS), a large longitudinal study that tracks the health services that Americans use. Any person with a diagnosis of depression disorder was identified in the MEPS files.

Over the duration of the study, on average there were 17.47 million adult patients diagnosed with depression each year with two years of follow-up, and 57.6 per cent of these received treatment with antidepressant medications.

The use of antidepressants was associated with some improvement in the mental component of SF-12 -- the survey tracking health-related quality of life. However, when this positive change was compared to the change in a group of people who were diagnosed with the depressive disorder but did not take antidepressants, there was no statistically significant association of antidepressants with either the physical (p=0.9595) or mental (p=0.6405) component of SF-12. In other words, the change in the quality of life seen among those on antidepressants over two years was not significantly different from that seen among those not taking the drugs.

The study was not able to separately analyze any subtypes or varying severities of depression. The authors say that future studies should investigate the use of non-pharmacological depression interventions used in combination with antidepressants.

The authors add: "Although we still need our patients with depression to continue using their antidepressant medications, long-term studies evaluating the actual impact of pharmacological and non-pharmacological interventions on these patients' quality of life is needed. With that being said, the role of cognitive and behavioural interventions in the long term-management of depression needs to be further evaluated in an effort to improve the ultimate goal of care for these patients; improving their overall quality of life." (ANI)

No Result
View All Result
  • Home
  • Latest News
  • National
  • International
  • Entertainment
  • Politics
  • Sports
  • Business
  • More
    • Health
    • Lifestyle
    • Technology
    • Science