Tuesday, July 8, 2025
  • English
  • Marathi
No Result
View All Result
Daily PRABHAT
  • Home
  • Latest News
  • National
  • International
  • Entertainment
  • Politics
  • Sports
  • Business
  • More
    • Health
    • Lifestyle
    • Technology
    • Science
Daily PRABHAT
No Result
View All Result
  • Home
  • Latest News
  • National
  • International
  • Entertainment
  • Politics
  • Sports
  • Business
  • More
Home Headlines

Good News : Researchers identify potential new treatment for COVID-19

by Digital Desk
4 years ago
in Headlines, International, Top News
A A
WORRYING : 36,446 new COVID-19 cases, 1,106 fatalities in Russia
Share on FacebookShare on Twitter

Canterbury [UK] – Researchers during a recent study identified a potential new treatment that suppresses the replication of SARS-CoV-2, the virus that causes Covid-19.

In order to multiply, all viruses, including coronaviruses, infect cells and reprogramme them to produce novel viruses. The study ‘Targeting the pentose phosphate pathway for SARS-CoV-2 therapy’ has been published by the scientific journal Metabolite.

The research revealed that cells infected with SARS-CoV-2 can only produce novel coronaviruses when their metabolic pentose phosphate pathway is activated.

When applying the drug benfooxythiamine, an inhibitor of this pathway, SARS-CoV-2 replication was suppressed and infected cells did not produce coronaviruses.

The research from the University of Kent’s School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, found the drug also increased the antiviral activity of ‘2-deoxy-D-glucose’; a drug which modifies the host cell’s metabolism to reduce virus multiplication.

This shows that pentose phosphate pathway inhibitors like benfooxythiamine are a potential new treatment option for COVID-19, both on their own and in combination with other treatments.

Additionally, Benfooxythiamin’s antiviral mechanism differs from that of other COVID-19 drugs such as remdesivir and molnupiravir. Therefore, viruses resistant to these may be sensitive to benfooxythiamin.

Professor Martin Michaelis, University of Kent, said, “This is a breakthrough in the research of COVID-19 treatment. Since resistance development is a big problem in the treatment of viral diseases, having therapies that use different targets is very important and provides further hope for developing the most effective treatments for COVID-19.”

“Targeting virus-induced changes in the host cell metabolism is an attractive way to interfere specifically with the virus replication process,” added Professor Jindrich Cinatl from Goethe-University Frankfurt

Tags: covid 19international
ShareTweetSendShareSend

Latest News

Sean ‘Diddy’ Combs gets standing ovation from fellow inmates after court verdict

A look at ‘Pehla Tu Duja Tu’ song from Ajay Devgn, Mrunal Thakur-starrer ‘Son of Sardaar 2’

Last-minute goals: When seconds shape emotions and rewrite fates

“We were overjoyed when he took 10 wickets..did not remember my problem”: Akash Deep’s sister, who is battling cancer

Andhra: YS Sharmila slams Jagan, Avinash Reddy over COA row; demands urgent action for Kadapa architecture students

Delhi: Interstate gang of bag lifters active on trains, railway premises busted; 4 held

Gujarat tops nation with notable increase of more than 241 sq kms in tree cover outside notified forest areas: FSI report

National Herald money laundering case: Donation to a party not for specific purpose, argues counsel for accused

BHU signs MoU with private firm for commercialisation of Curcumin patent

“Law and order in Bihar has completely collapsed”: Union Minister Chirag Paswan

Canterbury [UK] - Researchers during a recent study identified a potential new treatment that suppresses the replication of SARS-CoV-2, the virus that causes Covid-19. In order to multiply, all viruses, including coronaviruses, infect cells and reprogramme them to produce novel viruses. The study 'Targeting the pentose phosphate pathway for SARS-CoV-2 therapy' has been published by the scientific journal Metabolite. The research revealed that cells infected with SARS-CoV-2 can only produce novel coronaviruses when their metabolic pentose phosphate pathway is activated. When applying the drug benfooxythiamine, an inhibitor of this pathway, SARS-CoV-2 replication was suppressed and infected cells did not produce coronaviruses. The research from the University of Kent's School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, found the drug also increased the antiviral activity of '2-deoxy-D-glucose'; a drug which modifies the host cell's metabolism to reduce virus multiplication. This shows that pentose phosphate pathway inhibitors like benfooxythiamine are a potential new treatment option for COVID-19, both on their own and in combination with other treatments. Additionally, Benfooxythiamin's antiviral mechanism differs from that of other COVID-19 drugs such as remdesivir and molnupiravir. Therefore, viruses resistant to these may be sensitive to benfooxythiamin. Professor Martin Michaelis, University of Kent, said, "This is a breakthrough in the research of COVID-19 treatment. Since resistance development is a big problem in the treatment of viral diseases, having therapies that use different targets is very important and provides further hope for developing the most effective treatments for COVID-19." "Targeting virus-induced changes in the host cell metabolism is an attractive way to interfere specifically with the virus replication process," added Professor Jindrich Cinatl from Goethe-University Frankfurt
No Result
View All Result
  • Home
  • Latest News
  • National
  • International
  • Entertainment
  • Politics
  • Sports
  • Business
  • More
    • Health
    • Lifestyle
    • Technology
    • Science